Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/24770
Title: Muscle weakness, spasticity and disuse contribute to demineralization and geometric changes in the radius following chronic stroke
Authors: Pang, MYC 
Ashe, MC
Eng, JJ
Keywords: Bone density
Cerebrovascular accident
Osteoporosis
Rehabilitation
Issue Date: 2007
Publisher: Springer London Ltd
Source: Osteoporosis international, 2007, v. 18, no. 9, p. 1243-1252 How to cite?
Journal: Osteoporosis International 
Abstract: Summary: Bone health status of the radius in individuals with chronic stroke was evaluated using peripheral quantitative computed tomography. Bone mineral density and cortical thickness on the affected side were compromised when compared with the unaffected side. Muscle weakness, spasticity, and disuse were identified as contributing factors to such changes. Introduction: Following a stroke, demineralization and geometric changes occur in bone as a result of disuse and residual impairments, and these can contribute to an increased risk of fragility fractures. Methods: This study used peripheral quantitative computed tomography (pQCT) to evaluate volumetric bone mineral density and geometry at the midshaft radius in people living with chronic stroke. Older individuals with chronic stroke were recruited. Each subject underwent a pQCT scan of the midshaft radius at the 30% site on both upper limbs. Muscle strength, motor function, spasticity, and chronic disuse were also evaluated. Data from 47 subjects (19 women) were assessed. Results: A significant difference was found between the two limbs for cortical bone mineral content, cortical bone mineral density, cortical thickness, and polar stress-strain index. There was no significant side-to-side difference in total bone area. Percent side-to-side difference in muscle strength, spasticity, and chronic disuse were significant determinants of percent side-to-side difference in cortical bone mineral content and cortical thickness. Conclusions: The findings suggest that following chronic stroke, endosteal resorption of the midshaft radius occurred with a preservation of total bone area. Muscle weakness, spasticity, chronic disuse significantly contributed to demineralization and geometric changes in the radius following chronic stroke.
URI: http://hdl.handle.net/10397/24770
DOI: 10.1007/s00198-007-0372-6
Appears in Collections:Journal/Magazine Article

Access
View full-text via PolyU eLinks SFX Query
Show full item record

SCOPUSTM   
Citations

41
Last Week
1
Last month
0
Citations as of Sep 19, 2017

WEB OF SCIENCETM
Citations

35
Last Week
0
Last month
0
Citations as of Sep 11, 2017

Page view(s)

48
Last Week
3
Last month
Checked on Sep 18, 2017

Google ScholarTM

Check

Altmetric



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.