Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/23422
Title: A novel green gelatin-agar microencapsulation system with P. urinaria as an improved anti-A. niger model
Authors: Lam, PL
Kok, SHL
Ho, YW
Wong, RSM
Cheng, GYM
Cheng, CH
Lam, KH
Gambari, R
Lee, KKH
Chui, CH
Keywords: Agar
Aspergillus niger
Gelatin
Microcapsules
Phyllanthus urinaria
Issue Date: 2013
Publisher: Elsevier Sci Ltd
Source: Carbohydrate polymers, 2013, v. 92, no. 1, p. 877-880 How to cite?
Journal: Carbohydrate Polymers 
Abstract: In this study, a novel green microencapsulation system was used to develop Phyllanthus urinaria (PU) extract containing microcapsules. Agar was used with gelatin as the wall matrix materials of microcapsules to prevent the use of toxic crosslinker formaldehyde. Microencapsulated PU extract was developed to improve the potential antifungal activities of PU water extracts. The active components and surface morphology of PU extract containing microcapsules were analyzed by liquid chromatography/mass spectrometry and scanning electron microscopy, respectively. The in vitro release study demonstrated that approximately 80% of drug was released after 120 h. PU loaded microcapsules were shown to have a stronger anti-Aspergillus niger activity than the free drug.
URI: http://hdl.handle.net/10397/23422
ISSN: 0144-8617
DOI: 10.1016/j.carbpol.2012.09.080
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