Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/2321
DC Field | Value | Language |
---|---|---|
dc.contributor | Department of Applied Biology and Chemical Technology | - |
dc.creator | Kwok, CY | - |
dc.creator | Wong, CNY | - |
dc.creator | Yau, M | - |
dc.creator | Yu, PH | - |
dc.creator | Au, ALS | - |
dc.creator | Poon, CCW | - |
dc.creator | Seto, SW | - |
dc.creator | Lam, TY | - |
dc.creator | Kwan, YW | - |
dc.creator | Chan, SW | - |
dc.date.accessioned | 2014-12-11T08:29:03Z | - |
dc.date.available | 2014-12-11T08:29:03Z | - |
dc.identifier.issn | 1756-4646 | - |
dc.identifier.uri | http://hdl.handle.net/10397/2321 | - |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | Journal of Functional Foods © 2010 Elsevier Ltd. The journal web site is located at http://www.sciencedirect.com. | en_US |
dc.subject | Cholesterol | en_US |
dc.subject | Crataegus pinnatifida | en_US |
dc.subject | Dietary supplement | en_US |
dc.subject | Hawthorn | en_US |
dc.subject | High-fat diet | en_US |
dc.subject | Rat | en_US |
dc.title | Consumption of dried fruit of Crataegus pinnatifida (hawthorn) suppresses high-cholesterol diet-induced hypercholesterolemia in rats | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.description.otherinformation | Author name used in this publication: Mabel Yin-Chun Yau | en_US |
dc.description.otherinformation | Author name used in this publication: Peter Hoi-Fu Yu | en_US |
dc.identifier.spage | 179 | - |
dc.identifier.epage | 186 | - |
dc.identifier.volume | 2 | - |
dc.identifier.issue | 3 | - |
dc.identifier.doi | 10.1016/j.jff.2010.04.006 | - |
dcterms.abstract | The hypocholesterolemic and atheroscleroprotective potentials of dietary consumption of hawthorn (dried fruit of Crataegus pinnatifida, Shan Zha) were investigated by monitoring plasma lipid profiles and aortic relaxation in Sprague–Dawley rats fed with either normal diet, high-cholesterol diet (HCD) or HCD supplemented with hawthorn powder (2%, w/w) (4 weeks). In HCD-fed rats, an increased plasma total cholesterol and LDL-cholesterol with a decreased HDL-cholesterol was observed, and consumption of hawthorn markedly suppressed the elevated total cholesterol and LDL-lipoprotein levels plus an increased HDL-cholesterol level. The blunted acetylcholine-induced, endothelium-dependent relaxation of isolated aortas of HCD-fed rats was improved by hawthorn. The development of fatty liver, an increased nitric oxide synthase (NOS) activity and an elevated oxidative stress (as estimated by the attenuated levels of anti-oxidant enzymes) associated with HCD were attenuated by hawthorn. Thus, the results demonstrated that hawthorn consumption provides overall beneficial effects on reversing HCD associated detrimental changes. | - |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Journal of functional foods, July 2010, v. 2, no.3, p. 179-186 | - |
dcterms.isPartOf | Journal of functional foods | - |
dcterms.issued | 2010-07 | - |
dc.identifier.isi | WOS:000208625400002 | - |
dc.identifier.scopus | 2-s2.0-77955655682 | - |
dc.identifier.rosgroupid | r48841 | - |
dc.description.ros | 2009-2010 > Academic research: refereed > Publication in refereed journal | - |
dc.description.oa | Accepted Manuscript | en_US |
dc.identifier.FolderNumber | OA_IR/PIRA | en_US |
dc.description.pubStatus | Published | en_US |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Manuscript_revised.pdf | Pre-published version | 201.49 kB | Adobe PDF | View/Open |
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