Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/22037
Title: Label-free DNA sensor based on organic thin film transistors
Authors: Yan, F 
Mok, SM
Yu, J
Chan, HLW 
Yang, M
Keywords: DNA sensor
Organic semiconductor
Organic thin film transistor
Issue Date: 2009
Publisher: Elsevier
Source: Biosensors and bioelectronics, 2009, v. 24, no. 5, p. 1241-1245 How to cite?
Journal: Biosensors and bioelectronics 
Abstract: Organic thin film transistors (OTFTs) are excellent candidates for the application on disposable sensors due to their potentially low-cost fabrication process. A novel DNA sensor based on OTFTs with semiconducting polymer poly(3-hexylthiophene) has been fabricated by solution process. Both single- and double-strand DNA molecules are immobilized on the surface of the Au source/drain electrodes of different OTFT devices, producing a dramatic change in the performance of the devices, which is attributed to the increase of the contact resistances at the source/drain electrodes. Single-strand DNA and double-strand DNA are differentiated successfully in the experiments indicating that this is a promising technique for sensing DNA hybridization without labelling.
URI: http://hdl.handle.net/10397/22037
ISSN: 0956-5663
EISSN: 1873-4235
DOI: 10.1016/j.bios.2008.07.030
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