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Title: Validity of axial length measurements for monitoring myopic progression in orthokeratology
Authors: Cheung, SW
Cho, P 
Issue Date: 2013
Publisher: Association for Research in Vision and Ophthalmology
Source: Investigative ophthalmology and visual science, 2013, v. 54, no. 3, p. 1613-1615 How to cite?
Journal: Investigative ophthalmology and visual science 
Abstract: Purpose. To investigate the short-term effect of orthokeratology (ortho-k) lens wear on the anterior segment length for validating the use of axial length for monitoring myopic progression after ortho-k treatment. Methods. Thirty-seven and 39 subjects (ages: 7-10 years) were randomly assigned to wear ortho-k and single-vision spectacles, respectively. Central corneal thickness (CCT), anterior chamber depth (ACD), crystalline lens thickness (LT), and anterior segment length (ASL: summation of CCT, ACD, and LT) were measured before and 6 months after the treatment under cycloplegia. Changes in these parameters were evaluated and compared between the two groups of subjects. Results. There were no significant between-group differences in the baseline data (P > 0.37). After 6 months of lens wear, in the ortho-k group, CCT was significantly reduced by 0.009 ± 0.009 mm (P < 0.001), whereas ACD and LT remained unchanged (P > 0.15). In the spectacle group, ACD was significantly increased by 0.01 ± 0.03 mm (P = 0.008), whereas CCT and LT remained unchanged (P > 0.06). In both groups of subjects, ASL did not appreciably change but axial length was significantly increased by 0.10 ± 0.10 mm and 0.20 ± 0.11 mm in the ortho-k and the spectacle groups, respectively (P < 0.001). Conclusions. Eyeball elongation occurred in children wearing both ortho-k and single-vision spectacles. Since ASL was not affected by ortho-k treatment, axial length measured reflects the true growth of the eyeball and is a valid parameter for monitoring myopic progression in ortho-k treated eyes.
ISSN: 0146-0404
EISSN: 1552-5783
DOI: 10.1167/iovs.12-10434
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