Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/21601
Title: Effect of laser acupuncture therapy on bone and articular cartilage under simulated microgravity
Authors: Wang, Q
Guo, X 
Wang, XY
Liu, MQ
Zhang, M 
Zheng, YP 
Man, HC 
Keywords: Articular cartilage
Bone
Laser acupuncture
Simulated microgravity
Issue Date: 2010
Source: IFMBE Proceedings, 2010, v. 31 IFMBE, p. 852-855 How to cite?
Abstract: The objectives of this study are to investigate the changes in bone and articular cartilage in rat femur under 4-week tail suspension and to evaluate the therapeutic effects of laser acupuncture (LA). 18 rats were assigned into three groups. Group control (C) was under normal earth gravity, group tail-suspension (T) underwent tail suspension (TS) for 4 weeks, and group laser-acupuncture-therapy (L) were treated using LA at Yongquan (KI-1) and Housanli (ST-36) acupoint on left hindlimb during TS. Bone mineral density (BMD) was quantified by peripheral computed tomography (pQCT) and the thickness of articular cartilage was measured by high-resolution ultrasound biomicroscopy (UBM) before and after TS. It was found that TS resulted in a significant decrease in BMD of femoral distal metaphysis (p < 0.01) and femoral shaft (p < 0.05) and significant cartilage thinning at medial femoral condyle and patella (p < 0.05). With LA therapy, an increase was found in BMD and cartilage thickness. The histological stains show an evidence of the changes including trabecular rarefaction, and cartilage thinning, proteoglycan loss and cell clustering in articular cartilage in group T as well as the corresponding therapeutic effects of LA in group L. This study demonstrates that the 4-week simulated microgravity has negative effects on bone and articular cartilage while LA has therapeutic improvement on the quality of the tissues.
Description: 6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech, Singapore, 1-6 August 2010
URI: http://hdl.handle.net/10397/21601
ISBN: 9783540790389
ISSN: 1680-0737
DOI: 10.1007/978-3-642-14515-5_217
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