Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/21025
Title: A neuromusculoskeletal model to simulate the constant angular velocity elbow extension test of spasticity
Authors: Koo, TKK
Mak, AFT
Keywords: Constant angular velocity extension
Elbow spasticity
Neuromusculoskeletal modeling
Stretch reflex
Issue Date: 2006
Publisher: Elsevier
Source: Medical engineering & physics, 2006, v. 28, no. 1 spec. iss., p. 60-69 How to cite?
Journal: Medical engineering & physics 
Abstract: We developed a neuromusculoskeletal model to simulate the stretch reflex torque induced during a constant angular velocity elbow extension by tuning a set of physiologically-based parameters. Our model extended past modeling efforts in the investigation of elbow spasticity by incorporating explicit musculotendon, muscle spindle, and motoneuron pool models in each prime elbow flexor. We analyzed the effects of changes in motoneuron pool and muscle spindle properties as well as muscle mechanical properties on the biomechanical behavior of the elbow joint observed during a constant angular velocity elbow extension. Results indicated that both motoneuron pool thresholds and gains could be substantially different among muscles. In addition, sensitivity analysis revealed that spindle static gain and motoneuron pool threshold were the most sensitive parameters that could affect the stretch reflex responses of the elbow flexors during a constant angular velocity elbow extension, followed by motoneuron pool gain, and spindle dynamic gain. It is hoped that the model will contribute to the understanding of the underlying mechanisms of spasticity after validation by more elaborate experiments, and will facilitate the future development of more specific treatment of spasticity.
URI: http://hdl.handle.net/10397/21025
ISSN: 1350-4533
DOI: 10.1016/j.medengphy.2005.03.012
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