Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/20596
Title: Total synthesis of cis, cis-ceratospongamide
Authors: Chen, Z
Deng, J
Ye, T 
Keywords: cis
cis-Ceratospongamide
Conformation
Macrocyclization
Synthesis
Issue Date: 2003
Source: Arkivoc, 2003, v. 2003, no. 7, p. 268-285 How to cite?
Journal: Arkivoc 
Abstract: A total synthesis of cis, cis-ceratospongamide 1 was accomplished via 4+3 fragment condensation, macrolactamization and subsequent cyclodehydration. Macrolactamization of both linear peptides 4a & 4b produced the corresponding cyclopeptide 3 as a mixture of two conformational isomers (cis, cis 3a and cis, trans 3b). Further oxazoline ring closure furnished the cis, cis-ceratospongamide 1 which is identical to the natural product.
URI: http://hdl.handle.net/10397/20596
ISSN: 1424-6376
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