Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/20053
Title: Total synthesis of largazole
Authors: Ren, Q
Dai, L
Zhang, H
Tan, W
Xu, Z
Ye, T 
Keywords: Antitumor
Cyclodepsipeptide
Largazole
Macrolactamization
Total synthesis
Issue Date: 2008
Publisher: Georg Thieme Verlag
Source: Synlett, 2008, no. 15, p. 2379-2383 How to cite?
Journal: Synlett 
Abstract: The stereocontrolled total synthesis of largazole was accomplished, unambiguously confirming its structure. Key steps included the use of the Nagao thiazolidinethione auxiliary for a diastereoselective acetate aldol reaction, thiazoline-thiazole formation, and macrolactamization by use of the Mukaiyama reagent.
URI: http://hdl.handle.net/10397/20053
ISSN: 0936-5214
EISSN: 1437-2096
DOI: 10.1055/s-2008-1078270
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