Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/20020
Title: The emerging role of miRNAs in combined cancer therapy
Authors: Yu, HW
Cho, WC
Keywords: Chemotherapy
Combined cancer therapy
Immunotherapy
MicroRNA
Radiotherapy
Issue Date: 2015
Publisher: Ashley Publications Ltd
Source: Expert opinion on biological therapy, 2015, v. 15, no. 7, p. 923-925 How to cite?
Journal: Expert opinion on biological therapy 
Abstract: MicroRNAs (miRNAs) control physiological and fundamental processes in cellular development and differentiation by modulating the expression of their target genes. They have been found to participate in cell transformation and multiplication by functioning as oncomiRs and tumor suppressors in diverse cancers. Introduction of antisense miRNAs (antagomiRs) into primary cells such as immune cells by lipofection, viral vectors or electroporation can achieve the specific silencing of individual miRNAs. Therefore, harnessing miRNAs may lead to promising cancer therapeutics. There is emerging evidence demonstrating the involvement of miRNAs in combined cancer therapies, including chemotherapy, radiotherapy and immunotherapy combining with miRNA therapy.
URI: http://hdl.handle.net/10397/20020
ISSN: 1471-2598
DOI: 10.1517/14712598.2015.1030390
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