Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/18241
Title: Two new phenylpropanoids and one new sesquiterpenoid from the bioactive fraction of Sambucus williamsii
Authors: Xiao, HH
Dai, Y
Wong, MS 
Yao, XS
Keywords: Caprifoliaceae
Phenylpropanoid
Proliferation effects
Sambucus williamsii
Sesquiterpenoid
UMR 106 cells
Issue Date: 2015
Publisher: Taylor and Francis Ltd.
Source: Journal of Asian natural products research, 2015, v. 17, no. 6, p. 625-632 How to cite?
Journal: Journal of Asian Natural Products Research 
Abstract: Two new phenylpropanoids, samwirin (1) and samwiphenol (2), and a new sesquiterpenoid, 2β,4β,10α-trihydroxy-1αH,5βH-guaia-6-ene (3), together with six known compounds were isolated from the bioactive fraction of Sambucus williamsii Hance. Their structures including the absolute configurations were characterized on the basis of extensive 1D, 2D-NMR, MS, and CD spectral data. In vitro proliferation effects of all compounds on osteoblast-like UMR 106 cells were examined. Compounds 1, 4-9 significantly promoted cell proliferation. Compounds 5, 6, and 8 increased osteoblastic cell numbers separately by 24.3%, 25.2%, and 29.1% at 10-10 M, 10-10 M, and 10-8 M, respectively.
URI: http://hdl.handle.net/10397/18241
ISSN: 1028-6020
DOI: 10.1080/10286020.2015.1046448
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