Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/16810
Title: Discovery of diagnostic serum biomarkers of gastric cancer using proteomics
Authors: Lam, KWK
Lo, SCL 
Issue Date: 2008
Source: Proteomics : clinical applications, 2008, v. 2, no. 2, p. 219-228
Abstract: Gastric cancer has significant morbidity and mortality worldwide and locally. Good prognosis relies on an early diagnosis. However, this remains a challenge due to the lack of specific and sensitive serum biomarkers for early detection. Hence, there is a constant search for these biomarkers for screening purposes. Proteomic profiling enables a new approach to the discovery of biomarkers in disease. This review presents recent attempts in search of gastric cancer serum biomarker using proteomics. Different methodologies and different types of samples were employed by different groups of researchers. Major difficulties were encountered in the discovery processes, including interference from abundant proteins and continuous changing serum proteomes from different individuals.
Keywords: Biomarker
Gastric cancer
Publisher: Wiley-VCH
Journal: Proteomics : clinical applications 
ISSN: 1862-8346
EISSN: 1862-8354
DOI: 10.1002/prca.200780015
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