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Title: Characterization of the colorectal cancer in a rabbit model using quantitative high-frequency endoscopic ultrasound
Authors: Liu, C
Yang, Y
Sun, L 
Huang, CC
Keywords: Colorectal cancer (CRC)
Endoscopic ultrasound (EUS)
Quantitative ultrasound (QUS) characterization
Rabbit colorectal cancer model
Issue Date: 2013
Publisher: IEEE
Source: 2013 IEEE International Ultrasonics Symposium (IUS), 21-25 July 2013, Prague, p. 891-894 How to cite?
Abstract: Colorectal cancer (CRC) at early stage often has no symptoms, which causes delay of successful treatments. Colonoscopy is clinically performed for screening, during which biopsy may be conducted; however, it is difficult to determine early stage CRC by ordinary endoscopy even with dye due to the insufficient superficial scope of colorectal surface for pre-cancerous diagnosis. Endoscopic ultrasound (EUS) has been widely used to visualize overall depth-view five-layered structural alteration of colorectal tract. The field of knowledge of high-frequency EUS with quantitative ultrasound (QUS) for early colorectal cancer diagnosis is yet to be fully determined and a reproducible and feasible animal model is appropriate for further development of this novel modality. VX2 CRC Rabbit model is first time used as a model for endoscopic ultrasound imaging according to our knowledge. In this study, we for the first time show the application of high-frequency EUS along with QUS to characterize malignant colorectal tumor and benign colorectal tissue in a rabbit model of VX2 colorectal cancer.
ISBN: 978-1-4673-5684-8
ISSN: 1948-5719
DOI: 10.1109/ULTSYM.2013.0229
Appears in Collections:Conference Paper

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