Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/16200
Title: Recent advances in Cordyceps sinensis polysaccharides : mycelial fermentation, isolation, structure, and bioactivities: A review
Authors: Yan, JK
Wang, WQ
Wu, JY 
Keywords: Bioactivity
Cordyceps sinensis
Extraction
Polysaccharide
Production
Structural elucidation
Issue Date: 2014
Publisher: Elsevier Science Bv
Source: Journal of functional foods, 2014, v. 6, no. 1, p. 33-47 How to cite?
Journal: Journal of Functional Foods 
Abstract: Cordyceps (Ophiocordyceps sinensis) sinensis, the Chinese caterpillar fungus, is a unique and precious medicinal fungus in traditional Chinese medicine which has been used as a prestigious tonic and therapeutic herb in China for centuries. Polysaccharides are bioactive constituents of C. sinensis, exhibiting several activities such as immunomodulation, antitumour, antioxidant and hypoglycaemic. As natural C. sinensis fruiting body-caterpillar complexes are very rare and expensive, the polysaccharides documented over the last 15-20. years from this fungal species were mostly extracted from cultivated fungal mycelia (intracellular polysaccharides) or from mycelial fermentation broth (exopolysaccharides). Extraction and purification of the polysaccharides is a tedious process involving numerous steps of liquid and solid phase separations. Nevertheless, a large number of polysaccharide structures have been purified and elucidated. However, relationships between the structures and activities of these polysaccharides are not well established. This review provides a comprehensive summary of the most recent developments in various aspects (i.e., production, extraction, structure, and bioactivity) of the intracellular and exopolysaccharides from mycelial fermentation of C. sinensis fungi. The contents and data will serve as useful references for further investigation, production and application of these polysaccharides in functional foods and therapeutic agents.
URI: http://hdl.handle.net/10397/16200
ISSN: 1756-4646
DOI: 10.1016/j.jff.2013.11.024
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