Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/16173
Title: Computerized wrist pulse signal diagnosis using modified auto-regressive models
Authors: Chen, Y
Zhang, L 
Zhang, D 
Zhang, D
Keywords: Auto-regressive model
Time series analysis
Wrist pulse signal
Issue Date: 2011
Publisher: Springer
Source: Journal of medical systems, 2011, v. 35, no. 3, p. 321-328 How to cite?
Journal: Journal of medical systems 
Abstract: The wrist pulse signals can be used to analyze a person's health status in that they reflect the pathologic changes of the person's body condition. This paper aims to present a novel time series analysis approach to analyze wrist pulse signals. First, a data normalization procedure is proposed. This procedure selects a reference signal that is 'closest' to a newly obtained signal from an ensemble of signals recorded from the healthy persons. Second, an auto-regressive (AR) model is constructed from the selected reference signal. Then, the residual error, which is the difference between the actual measurement for the new signal and the prediction obtained from the AR model established by reference signal, is defined as the disease-sensitive feature. This approach is based on the premise that if the signal is from a patient, the prediction model previously identified using the healthy persons would not be able to reproduce the time series measured from the patients. The applicability of this approach is demonstrated using a wrist pulse signal database collected using a Doppler Ultrasound device. The classification accuracy is over 82% in distinguishing healthy persons from patients with acute appendicitis, and over 90% for other diseases. These results indicate a great promise of the proposed method in telling healthy subjects from patients of specific diseases.
URI: http://hdl.handle.net/10397/16173
ISSN: 0148-5598
EISSN: 1573-689X
DOI: 10.1007/s10916-009-9368-4
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