Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/16136
Title: Micro chip with nanostructured membranes for cell morphology monitoring
Authors: Yu, J
Chao, C
Cheng, CH 
Liu, Q
Xiao, L
Yang, M 
Keywords: KYSE30 human oesophageal cancer cells
Microcell chip
Nanoporous alumina menbrane
Impedance spectroscopy
Issue Date: 2007
Publisher: IEEE
Source: 7th IEEE Conference on Nanotechnology, 2007 : IEEE-NANO 2007, 2-5 August 2007, Hong Kong, p. 304-307 How to cite?
Abstract: We present a novel nanostructured micro cell chip with impedance spectroscopy for monitoring cell morphology change non-invasively, in real time and independent of any fluorescent or radioactive probes. The key strategy is to integrate the nanoporous alumina membrane with silicon based microfluidic devices for the impedance monitoring. In this configuration, the impedance of even single cell can be measured at the low frequency range but not be affected by the electrode polarization. The KYSE30 human oesophageal cancer cells have been successfully cultured on nanoporous alumina membrane. Initial electrochemical experiments with lipid layers have been done to testify the functionality of this device. Further experiments for cancer cells will be explored in near future.
URI: http://hdl.handle.net/10397/16136
ISBN: 978-1-4244-0607-4
978-1-4244-0608-1 (E-ISBN)
DOI: 10.1109/NANO.2007.4601195
Appears in Collections:Conference Paper

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