Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/15918
Title: Modeling the bifurcating flow in a human lung airway
Authors: Liu, Y 
So, RMC 
Zhang, CH
Keywords: Bifurcating flow
Human lung
Three-dimensional modeling
Issue Date: 2002
Publisher: Elsevier
Source: Journal of biomechanics, 2002, v. 35, no. 4, p. 465-473 How to cite?
Journal: Journal of biomechanics 
Abstract: The inspiratory flow characteristics in a three-generation lung airway have been numerically investigated using a control volume method to solve the fully three-dimensional laminar Navier-Stokes equations. The three-generation airway is extracted from the fifth to seventh branches of the model of Weibel (Morphometry of the Human Lung, Academic Press, New York, Springer, Berlin, 1963) with in-plane and 90° off-plane configurations. Computations are carried out in the Reynolds number range of 200-1600, corresponding to mouth-air breathing rates ranging from 0.27 to 2.16l/s, or an averaged height of a man breathing from quiet to vigorous state. Particular attention is paid to establishing relations between the Reynolds number and the overall flow characteristics, including flow patterns and pressure drop. The ratio of airflow rate through the medial branch to that of the lateral branch for an in-plane airway increases as Re 0.227. However, the total pressure drop coefficient varies as Re -0.497 for an in-plane airway and as Re -0.464 for an off-plane airway. These pressure drop results are in good agreement with the experimentally measured behavior of Re -0.5 and are more accurate than the numerically determined behavior of Re -0.61 assuming the airways to be approximated by two-dimensional channels.
URI: http://hdl.handle.net/10397/15918
ISSN: 0021-9290
DOI: 10.1016/S0021-9290(01)00225-1
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