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Title: Antioxidant and hypoglycemic activities of exopolysaccharide by submerged culture of inocutus hispidus
Authors: Liu, SH
Sun, SW
Tian, ZF
Wu, JY 
Li, XL
Xu, CP
Keywords: Antioxidant
Hypoglycemic effect
Inocutus hispidus
Issue Date: 2015
Publisher: Medknow Publications
Source: Indian journal of pharmaceutical sciences, 2015, v. 77, no. 3, p. 361-365 How to cite?
Journal: Indian Journal of Pharmaceutical Sciences 
Abstract: This work was to investigate the hypoglycemic and antioxidant activities of the exopolysaccharides produced in a stirred-tank bioreactor by Inocutus hispidus. The exopolysaccharides showed significant antioxidant activities, up to 70.7±2.5% inhibition of hydroxyl radicals, 50% inhibition of 2,2-diphenyl-1-picrylhydrazyl radicals, and a Trolox equivalent antioxidant capacity of 3.3 mM. The exopolysaccharide also showed notable hypoglycemic effects in streptozotocin-induced diabetic mice, reducing the plasma glucose, total cholesterol and triacylglycerol concentrations by 18.2±1.5, 20.9±0.8 and 14.4±0.4, respectively. The results demonstrated the potential of this EPS for human health protection against oxidative damage and hyperglycemia.
ISSN: 0250-474X
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