Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/14566
Title: Soy isoflavones and their bone protective effects
Authors: Zhang, Y
Chen, WF
Lai, WP
Wong, MS 
Keywords: Bone health
Breast cancer
Genistein
Osteoblastic functions
Postmenopausal osteoporosis
Soy isoflavones
Issue Date: 2008
Publisher: Springer
Source: Inflammopharmacology, 2008, v. 16, no. 5, p. 213-215 How to cite?
Journal: Inflammopharmacology 
Abstract: Several observational studies have suggested that populations with a high dietary soy intake have a lower incidence of osteoporosis-related fractures when compared to Western populations. However, there has not been consistent data to show that soy isoflavones protect against or lessen bone loss. Studies in our laboratory showed that genistein, the major soy isoflavone, could stimulate osteoblastic functions as well as human breast cancer cell growth. These studies raised the concern of whether it would be safe for women who have a prior history of breast cancer to consume soy isoflavone for management of postmenopausal osteoporosis. As increasing the purity of genistein is known to increase its ability to induce human breast cancer cell growth, current effort in our laboratory is to determine if the in vivo bone protective effects will be affected by the complexity of the soy isoflavones extract in ovariectomized mice.
URI: http://hdl.handle.net/10397/14566
ISSN: 0925-4692
EISSN: 1568-5608
DOI: 10.1007/s10787-008-8018-7
Appears in Collections:Journal/Magazine Article

Access
View full-text via PolyU eLinks SFX Query
Show full item record

SCOPUSTM   
Citations

28
Last Week
0
Last month
0
Citations as of Sep 11, 2017

Page view(s)

26
Last Week
1
Last month
Checked on Sep 18, 2017

Google ScholarTM

Check

Altmetric



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.