Please use this identifier to cite or link to this item:
Title: Concise synthesis of two natural steroidal glycosides isolated from Allium schoenoprasum
Authors: Liu, Q
Guo, T
Li, D
Li, W
Keywords: Cytotoxic activity
Glycosyl donors
Steroidal glycosides
Issue Date: 2015
Publisher: Kluwer Academic Publishers
Source: Research on chemical intermediates, 2015 How to cite?
Journal: Research on Chemical Intermediates 
Abstract: Two natural steroidal glycosides, diosgenin 3-O-α-l-rhamnopyranosyl-(1→2)-[β-d-glucopyranosyl-(1→4)]-β-d-glucopyranoside (1) and laxogenin 3-O-α-l-rhamnopyranosyl-(1→2)-[β-d-glucopyranosyl-(1→4)]-β-d-glucopyranoside (2) with important cytotoxic activity against the HCT 116 and HT-29 human colon cancer cell lines have been efficiently synthesized via straightforward sequential glycosylation reaction with the combined use of N-phenyltrifluoroacetimidates and trichloroacetimidates donors at room temperature. All structures of the synthesized new compounds were identified by 1H NMR, 13C NMR and HRMS spectra.
ISSN: 0922-6168
DOI: 10.1007/s11164-015-2106-2
Appears in Collections:Journal/Magazine Article

View full-text via PolyU eLinks SFX Query
Show full item record

Page view(s)

Last Week
Last month
Citations as of Feb 18, 2019

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.