Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/12332
Title: Room-temperature copper-catalyzed alpha-arylation of malonates
Authors: Yip, SF
Cheung, HY
Zhou, Z
Kwong, FY 
Issue Date: 2007
Publisher: American Chemical Society
Source: Organic letters, 2007, v. 9, no. 17, p. 3469-3472 How to cite?
Journal: Organic letters 
Abstract: An effective method in targeting alpha-aryl malonates is reported. In the presence of a catalytic amount of 2-picolinic acid and CuI, the coupling of aryl iodides with diethyl malonate proceeds smoothly even at room temperature. The high levels of functional group compatibility and exceptionally mild reaction conditions offer this an attractive protocol in accessing a variety of arylated malonates.
URI: http://hdl.handle.net/10397/12332
ISSN: 1523-7060
EISSN: 1523-7052
DOI: 10.1021/ol701473p
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