Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/11599
Title: Retinal nerve fiber layer thickness in normal Hong Kong Chinese children measured with optical coherence tomography
Authors: Leung, MMP
Huang, RYC
Lam, AKC 
Keywords: Children
Optical coherence tomography
Retinal nerve fiber layer thickness
Issue Date: 2010
Publisher: Lippincott Williams & Wilkins
Source: Journal of glaucoma, 2010, v. 19, no. 2, p. 95-99 How to cite?
Journal: Journal of Glaucoma 
Abstract: PURPOSE: To obtain the retinal nerve fiber layer (RNFL) thickness normative values of Hong Kong children by using optical coherence tomography (OCT) and to investigate the effect of age and axial length (AL) on RNFL thickness. PATIENTS AND METHODS: One hundred and four normal children aged between 6 and 17 years were recruited for this study. The RNFL thickness was measured by OCT (Stratus OCT). AL was measured by the IOLMaster. RESULTS: The median age of our subjects was 9.75 years (range: 6.08 to 17.58 years). The mean full circle peripapillary RNFL (RNFL-FC) was 113.5 μm (SD 9.8) and 113.1 μm (SD 10.8) in the right and left eyes, respectively. Multiple linear regression analysis showed a significant negative correlation between AL and RNFL-FC in both the right (r=-0.23, P<0.05) and left eyes (r=-0.25, P<0.05). The effect was the strongest in the superior quadrant. Every 1 mm increase in AL would result in a decrease in RNFL-FC by 2.7 to 2.9 μm. Age did not show significant effect on RNFL-FC. CONCLUSIONS: This study provides normative RNFL values for Hong Kong Chinese children. It can be used as a reference for the screening of glaucoma in children. AL demonstrates a significant negative correlation with RNFL thickness.
URI: http://hdl.handle.net/10397/11599
DOI: 10.1097/IJG.0b013e3181a98cfa
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