Precision and Perseverance: Tumor-Targeted Gene Editing Quest

Abstract

In the year of 2022, Avery Zhu embarked on a thrilling scientific quest with a project titled “pH-Responsive Peptide for Tumor Targeted Delivery of CRISPR-Cas9 Ribonucleoprotein. Guided by the brilliant Prof. Clarence Wong, he dove into the fascinating world of gene editing. The mission was to harness the power of pH-responsive peptides to deliver CRISPR/Cas9 into cancer cells, a task that proved to be as daunting as it was exciting. The greatest challenge lay in producing uncontaminated RNA, necessitating the creation of a sustainable manufacturing line. After six months of persistent trial and error, she finally triumphed. The unwavering support from Avery’s mentors and peers was essential, and the project culminated in a top-grade thesis. This journey not only expanded her scientific expertise but also strengthened her resilience and patience.