Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/11220
Title: Asymmetric trimethylsilylcyanation of acetophenone catalyzed by cinchona alkaloids
Authors: Choi, MCK
Chan, SS
Chan, MK
Kim, JC
Matsumoto, K
Issue Date: 2002
Source: Heterocycles, 2002, v. 58, p. 645-654
Abstract: Six cinchona alkaloids were used as catalysts for the study of addition of TMSCN to acetophenone (1) at atmospheric and pressurized conditions. Only the about 10% ee was attained either in hexane or ethyl acetate using quinine or cinchonine. The enantiomeric excesses (ee's) of the cyanohydrin cyanohydnn (3) were found to be decreased with pressure in the presence of alkaloids. The rationale of these reactions was discussed.
Publisher: Pergamon-Elsevier Science Ltd
Journal: Heterocycles 
ISSN: 0385-5414
Appears in Collections:Journal/Magazine Article

Access
View full-text via PolyU eLinks SFX Query
Show full item record

SCOPUSTM   
Citations

13
Last Week
0
Last month
Citations as of Aug 14, 2020

WEB OF SCIENCETM
Citations

12
Last Week
0
Last month
0
Citations as of Sep 28, 2020

Page view(s)

129
Last Week
1
Last month
Citations as of Sep 27, 2020

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.