Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/10515
Title: Fabrication and degradation of poly(l-lactic acid) scaffolds with wool keratin
Authors: Li, J
Li, Y 
Li, L
Mak, AFT
Ko, F
Qin, L
Keywords: A. Polymer-matrix composites (PMCs)
D. Infrared (IR) spectroscopy
D. Photoelectron spectroscopy (XPS)
Wool keratin
Issue Date: 2009
Publisher: Pergamon Press
Source: Composites. Part B, Engineering, 2009, v. 40, no. 7, p. 664-667 How to cite?
Journal: Composites. Part B, Engineering 
Abstract: As a natural protein, wool keratin was used to improve the cell affinity of poly(l-lactic acid) (PLLA). Small keratin particles were prepared from keratin solution by the spray-drying process. Keratin particles were blended with PLLA/1,4-dioxane solution and paraffin micro-spheres which were used as progens. After the mixture was molded and dried, the paraffin micro-spheres were removed by cyclohexane. PLLA/keratin scaffolds with controlled pore size and well interconnectivity were fabricated. Keratin releasing rate was detected by Fourier transform infrared (FTIR) after the scaffold was immersed into PBS up to 4 weeks. The surface chemical structure was examined by X-ray photoelectron spectroscope (XPS). The results suggested that the keratin could be held into the scaffold which was expected to improve the interactions between osteoblasts and the polymeric scaffolds.
URI: http://hdl.handle.net/10397/10515
ISSN: 1359-8368
EISSN: 1879-1069
DOI: 10.1016/j.compositesb.2009.04.012
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