Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/10013
Title: Effectiveness of no-rub contact lens cleaning on protein removal : a pilot study
Authors: Mok, KH
Cheung, RWL
Wong, BKH
Yip, KK
Lee, VWH
Keywords: Contact lens solution
Contacts lens cleaning
Multipurpose solution
No rub
Protein
Issue Date: 2004
Publisher: Lippincott Williams & Wilkins
Source: Optometry and vision science, 2004, v. 81, no. 6, p. 468-470 How to cite?
Journal: Optometry and vision science 
Abstract: Purpose. To compare the amount of protein deposits adhering to human-worn soft contact lenses, using the untreated contact lens from the contralateral eye as controls, to investigate the capabilities of the No Rub contact lens cleaning systems in protein removal from soft contact lenses. Methods. New 1 Day Acuvue soft contact lenses were worn on a daily-wear basis by 16 Hong Kong Chinese volunteers on 5 separate days. Four right lenses of each subject were treated with No Rub contact lens cleaning systems (Alcon Opti-Free Express, Alcon Opti-Free Express No Rub Lasting Comfort Formula, B&L ReNu MultiPlus, and Ciba Vision SOLO Care Plus). The total amount of protein was extracted from all contact lenses and analyzed by the Bradford assay. Results. Among the contralateral contact lenses, there was no significant difference in the total protein extracted (TPE; 11.2 ± 3.8 vs. 12.6 ± 5.2 mg/ml, p = 0.20). There was a significant positive correlation in TPE between two lenses worn by the same volunteer (R2 = 0.84, y = 0.79x + 1.3, p < 0.001). Lenses treated with Opti-Free Express and Opti-Free Express No Rub Lasting Comfort Formula solutions had significantly less TPE (7.3 ± 5.2 and 6.7 ± 4.1 mg/ml, respectively, p < 0.001) than the untreated contralateral lenses (12.7 ± 6.8 and 13.2 ± 5.3 mg/ml, respectively). No statistical difference in TPE was detected in the lenses treated with ReNu MultiPlus (13.0 ± 7.8 mg/ml, p = 0.49) and Solo Care Plus (12.1 ± 8.7 mg/ml, p = 0.99) solutions when compared with their untreated contralateral lenses (13.0 ± 7.8 and 12.1 ± 8.7 mg/ml, respectively). Conclusions. Not all no-rub contact lens solutions were shown capable of removing the protein deposit from soft contact lenses.
URI: http://hdl.handle.net/10397/10013
ISSN: 1040-5488
EISSN: 1538-9235
DOI: 10.1097/01.opx.0000135098.07502.9f
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